至亲 (zhì qīn) literally combines 至 (zhì), meaning 'utmost' or 'very', and 亲 (qīn), meaning 'relative' or 'kin'. Together, it denotes one's closest, most intimate blood relatives — typically parents, siblings, children, or sometimes grandparents. It carries a strong emotional and cultural weight in Chinese, reflecting Confucian values that emphasize familial hierarchy and deep affection within the immediate family circle.

This term is formal and respectful, often used in written language, speeches, obituaries, or serious conversations about family obligations and loyalty. It is not used for distant cousins or in-laws unless they are exceptionally close and treated as immediate family. Unlike more general terms like 家人 (jiārén, 'family members'), 至亲 highlights both biological closeness and profound emotional bond — it implies irreplaceable, unconditional ties.